Product Details
L-Carnitine — Research Grade, ≥98% Purity (HPLC)
Amino acid derivative. Mitochondrial fatty-acid transport cofactor. Lot-specific COA included.
L-Carnitine (levocarnitine) is a quaternary ammonium compound that serves as an essential cofactor for the transport of long-chain fatty acids from the cytosol into the mitochondrial matrix, where they undergo β-oxidation for ATP production. It is biosynthesized endogenously from the amino acids lysine and methionine and is also obtained from dietary sources. In research settings, L-carnitine is used as a tool compound to study mitochondrial function, lipid metabolism, and cellular energy homeostasis in both in vitro and in vivo models.
Supplied as a crystalline powder for laboratory research applications. Each lot is independently verified for purity and identity and ships with a Certificate of Analysis.
Specifications
| Parameter | Detail |
|---|---|
| CAS Number | 541-15-1 |
| Molecular Formula | C₇H₁₅NO₃ |
| Molecular Weight | 161.20 g/mol |
| Purity | ≥98% (HPLC) |
| Identity | Confirmed by mass spectrometry |
| Appearance | White crystalline powder |
| Solubility | H₂O: 29 mg/mL; Ethanol: 30 mg/mL; DMSO: 6.25 mg/mL |
| Storage | −20 °C, desiccated, protected from light |
| Format | Crystalline powder |
| Documentation | Lot-specific COA (HPLC + MS) |
Note: Solubility data vary by supplier and batch. Water solubility has been reported as high as 125 mg/mL in some formulations. Verify the specific solubility and purity for your lot against the Certificate of Analysis.
Research applications
L-Carnitine is used in laboratory settings to investigate:
-
Mitochondrial fatty-acid β-oxidation — transport of long-chain fatty acids across the inner mitochondrial membrane via the carnitine shuttle system in isolated mitochondria and cell culture models
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Oocyte maturation and embryonic development — effects on intracellular lipid content, reactive oxygen species (ROS) levels, and mitochondrial function during in vitro maturation (IVM) of porcine oocytes, with 0.6 mg/mL showing reduced lipid and ROS levels without impairing maturation
-
Hepatic stellate cell protection — attenuation of cisplatin-induced activation in LX-1 hepatic stellate cells via reduction of inflammatory cytokines, nitrosative stress, and extracellular matrix remodeling
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Stem cell survival and maintenance — promotion of cell survival and maintenance properties in gingiva-derived stem cell models
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Myogenic differentiation — combined treatment with oleate to facilitate biological activation of myogenic progenitors in myofiber regeneration research
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Metabolic pathway research — endogenous metabolite studies involving carnitine O-acetyltransferase and mitochondrial carnitine/acylcarnitine carrier proteins
Handling and storage
Store the lyophilized powder at −20 °C, desiccated and protected from light. L-Carnitine is freely soluble in water and ethanol; prepare stock solutions under aseptic conditions. Aliquot reconstituted solutions to avoid repeated freeze-thaw cycles. Powder is stable for up to 3 years at −20 °C; reconstituted solutions should be stored at −80 °C for longer-term use.
For laboratory use by qualified personnel only.




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