Product Details
NAD+ (Nicotinamide Adenine Dinucleotide, Oxidized Form) — Research Grade, ≥98% Purity (HPLC) NAD Peptide
Redox coenzyme. Electron carrier. Lyophilized powder. Lot-specific COA included.
NAD Peptide (β-nicotinamide adenine dinucleotide, oxidized form) is a dinucleotide coenzyme that functions as the primary electron carrier in cellular redox reactions. Together with its reduced form, NADH, it constitutes the NAD+/NADH redox pair central to oxidative phosphorylation, glycolysis, and a wide range of enzyme-catalyzed oxidation-reduction reactions. It also serves as a substrate for NAD+-consuming enzymes including sirtuins, PARPs, and CD38. NAD Peptide

The coenzyme is not a peptide. It is composed of two nucleotides — adenine and nicotinamide — linked by a pyrophosphate bond. It is supplied as a lyophilized powder for in vitro and preclinical research applications. Each lot is independently verified for purity and identity and ships with a Certificate of Analysis. NAD Peptide
Specifications
| Parameter | Detail |
|---|---|
| CAS Number | 53-84-9 |
| Molecular Formula | C₂₁H₂₇N₇O₁₄P₂ |
| Molecular Weight | 663.43 g/mol |
| Purity | ≥98% (HPLC) |
| Identity | Confirmed by mass spectrometry and NMR |
| Appearance | White to off-white solid |
| Solubility | Soluble in water and aqueous buffers |
| Storage | −20 °C (powder, 3 years); −80 °C (solution, 1 year) |
| Format | Lyophilized powder |
| Documentation | Lot-specific COA (HPLC + MS) |
Note: NAD+ is also available as a lithium salt (CAS 64417-72-7) and as the reduced form NADH (disodium salt, CAS 606-68-8). Verify the exact form and molecular weight against the Certificate of Analysis supplied with your lot.
Research applications
NAD+ is used in laboratory settings to investigate:
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Cellular redox metabolism — electron transfer in oxidative phosphorylation and glycolysis in mitochondrial and cell culture models
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Sirtuin and PARP pathway research — NAD+ availability as a substrate for sirtuins and poly(ADP-ribose) polymerases in cellular senescence and DNA repair studies
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Cellular senescence and aging research — replenishment of intracellular NAD+ levels and inhibition of senescence in periodontal ligament stem cells, with polyphenol-NAD+ nanoparticles effectively replenishing NAD+ and scavenging ROS
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Oocyte maturation research — NAD+ generated from nicotinamide mononucleotide (NMN) and its role in F-actin polymerization, spindle assembly, and oocyte quality in post-ovulatory aged porcine oocytes
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Acute brain injury and neuroprotection — NAD+ delivery to energy-depleted cells, with reports suggesting NAD+ can decrease neuronal death from oxygen-glucose deprivation and prevent mitochondrial depolarization
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Enzymatic assay development — NAD+/NADH quantification and dehydrogenase-coupled reaction systems for analytical method development
Handling and storage
Reconstitute under aseptic conditions using sterile water or an appropriate aqueous buffer. NAD+ is soluble in water. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles. Lyophilized powder is stable for up to 3 years at −20 °C or 2 years at 4 °C; reconstituted solutions are stable for 1 year at −80 °C or 6 months at −20 °C. nad peptide
NAD Peptide For laboratory use by qualified personnel only.








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