Product Details
Buy PEG MGF Peptide at PeptidesUnit.com: High-Purity Research Compound for Muscle Biology Studies
PEG MGF (Pegylated Mechano Growth Factor) is a synthetic research peptide engineered for laboratory investigations into satellite cell activation, muscle repair signaling, and growth factor pharmacokinetics. At PeptidesUnit.com, we supply high-purity PEG-MGF specifically for in-vitro and preclinical research applications.
Important Disclaimer: PEG MGF is sold strictly as a research chemical for laboratory investigation. It is not FDA-approved, not intended for human consumption, and prohibited by WADA for athletes subject to anti-doping testing .
What Is PEG MGF?
PEG MGF is a pegylated form of Mechano Growth Factor (MGF), a splice variant of Insulin-like Growth Factor-1 (IGF-1). Native MGF is produced locally in skeletal muscle in response to mechanical loading or damage and has an extremely short half-life of approximately 5–7 minutes . The PEGylation modification attaches a polyethylene glycol chain to the peptide, extending its half-life to several hours and enabling systemic distribution in experimental models .
The compound retains the 24-amino acid core sequence of MGF (YQPPSTNKNTKSQRRKGSTFEEHK) with the PEG moiety covalently attached, serving purely as a pharmacokinetic modifier .
PEG-MGF Specifications
| Parameter | Detail |
|---|---|
| Synonyms | Pegylated MGF, PEG IGF-1 Ec |
| Molecular Formula | C₁₂₁H₂₀₀N₄₂O₃₉ (peptide backbone) |
| Molecular Weight | ~2,948 Da (peptide core) |
| Purity | ≥95% (HPLC verified) |
| Appearance | White to off-white lyophilized powder |
| Solubility | Soluble in bacteriostatic water |
| Storage | -20°C for lyophilized powder |
Research Background
PEG MGF has been investigated in preclinical models for its proposed role in:
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Satellite cell activation: MGF is believed to activate muscle stem cells through a pathway distinct from the classical IGF-1 receptor
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Muscle repair mechanisms: Research examines how growth factor signaling influences myoblast proliferation and differentiation
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Peptide pharmacokinetics: The pegylated form serves as a model for studying how chemical modifications affect peptide stability and biodistribution
Critical research caveat: The evidence base for PEG-MGF remains entirely preclinical, consisting of cell culture and animal studies. No controlled human trials have established efficacy for any indication .
Why Researchers Choose PEG MGF from PeptidesUnit.com
At PeptidesUnit.com, we understand that reproducible research requires consistent, high-quality compounds. Every batch of PEG-MGF we supply undergoes rigorous quality control to ensure:
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High purity: ≥95% purity verified by HPLC analysis
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Accurate characterization: Confirmed molecular identity
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Proper storage: Shipped in conditions that maintain compound stability
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Transparent documentation: Certificate of Analysis available for each batch
How to Buy PEG MGF at PeptidesUnit.com
Purchasing PEG-MGF from PeptidesUnit.com is straightforward:
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Visit our product page for PEG-MGF
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Select your desired quantity (available in multiple milligram sizes)
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Complete checkout with secure payment options
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Receive your order with proper packaging and documentation
We prioritize discreet, efficient shipping with tracking information provided for every order.
Frequently Asked Questions
Is PEG MGF FDA-approved?
No. PEG-MGF is not approved by the FDA or any regulatory agency for human use. It is sold strictly as a research chemical for laboratory investigation .
What is PEG MGF used for in research?
PEG-MGF is primarily used to study satellite cell activation, muscle repair signaling pathways, and growth factor pharmacokinetics in preclinical models .
How should PEG-MGF be stored?
For maximum stability, store lyophilized PEG-MGF powder at -20°C, protected from light and moisture. Once reconstituted with bacteriostatic water, store at 2–8°C and use within 2–3 weeks. Do not freeze reconstituted solution .
Is PEG MGF prohibited in sports?
Yes. PEG-MGF is prohibited by WADA under category S2 (peptide hormones, growth factors, and related substances) at all times, both in-competition and out-of-competition .
What is the difference between MGF and PEG MGF?
Native MGF has a half-life of approximately 5–7 minutes and acts locally. PEG-MGF has a polyethylene glycol chain attached to extend its half-life to several hours and enable systemic distribution in research settings .
Research Applications for PEG MGF
Researchers are currently investigating PEG-MGF across multiple scientific domains:
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Muscle biology: Studying satellite cell activation and myoblast proliferation mechanisms
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Growth factor signaling: Mapping MGF-specific pathways distinct from IGF-1 receptor signaling
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Peptide engineering: Examining how PEGylation affects peptide stability and cellular uptake
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Tissue repair models: Investigating muscle regeneration in preclinical injury models
Order PEG MGF Today
Whether you are studying muscle repair mechanisms, satellite cell biology, or peptide pharmacokinetics, PEG-MGF from PeptidesUnit.com provides a reliable research tool for your laboratory.
Browse our catalog at PeptidesUnit.com to order PEG MGF and other high-quality research compounds. peg mgf peptide






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