Product Details

Buy KPV Peptide at PeptidesUnit.com: High-Purity Research Compound for Inflammation Studies

KPV (Lysine-Proline-Valine) is a naturally occurring tripeptide derived from the C-terminal fragment of α-melanocyte-stimulating hormone (α-MSH). At PeptidesUnit.com, we supply high-purity KPV specifically for laboratory research applications investigating inflammatory pathways and epithelial biology.

Important Disclaimer: KPV is sold strictly as a research chemical for laboratory investigation. It is not FDA-approved, not intended for human consumption, and has not undergone human clinical trials.

What Is KPV?

KPV Peptide is a short, three-amino-acid peptide with the sequence Lys-Pro-Val . Unlike its parent hormone α-MSH, KPV does not require melanocortin receptor binding to exert its proposed anti-inflammatory effects . This receptor-independent activity has made it a subject of interest in preclinical gastrointestinal and dermatological research.

The compound is notable for its oral stability and ability to be taken up by the PepT1 oligopeptide transporter, which is highly expressed in intestinal epithelial cells and upregulated during inflammation .

KPV Peptide Specifications

Research Background

KPV has been investigated in preclinical models for its potential role in:

• Gastrointestinal inflammation: In murine colitis models, KPV administration has been associated with reduced colonic myeloperoxidase activity and decreased pro-inflammatory cytokine expression

• Epithelial barrier function: Research examines how KPV modulates NF-κB signaling in intestinal epithelial cells

• Dermatological applications: Studies in keratinocyte models have explored KPV’s effects on inflammation and cell viability

• Corneal wound healing: Rabbit model research has investigated topical KPV application in corneal epithelial repair

Critical research caveat: The evidence base for KPV is entirely preclinical, consisting of cell culture and animal studies. No controlled human trials have established efficacy for any indication .

Regulatory Status (Important)

KPV Peptide is not FDA-approved for any human use. In 2026, the FDA’s Pharmacy Compounding Advisory Committee voted to recommend adding KPV to the 503A Bulks List, which would allow licensed compounding pharmacies to prepare it for patients with a prescription . This vote is non-binding, and the FDA has not issued a final decision. As of now, KPV is not reliably available through licensed US pharmacies .

Products sold online as “research use only” are not legal for human use and are not manufactured to pharmaceutical standards .

Why Researchers Choose KPV from PeptidesUnit.com

At PeptidesUnit.com, we understand that reproducible research requires consistent, high-quality compounds. Every batch of KPV we supply undergoes rigorous quality control to ensure:

• High purity: ≥98% purity verified by HPLC analysis

• Accurate characterization: Confirmed molecular identity and CAS number

• Proper storage: Shipped in conditions that maintain compound stability

• Transparent documentation: Certificate of Analysis available for each batch

How to Buy KPV at PeptidesUnit.com

Purchasing KPV from PeptidesUnit.com is straightforward:

1. Visit our product page for KPV

2. Select your desired quantity (available in multiple milligram sizes)

3. Complete checkout with secure payment options

4. Receive your order with proper packaging and documentation

We prioritize discreet, efficient shipping with tracking information provided for every order.

Frequently Asked Questions

Is KPV Peptide FDA-approved?
No. KPV is not approved by the FDA or any regulatory agency for human use. It is sold strictly as a research chemical for laboratory investigation .

What is KPV Peptide used for in research?
KPV is primarily used to study inflammatory pathways, epithelial barrier function, and NF-κB signaling in preclinical models .

How should KPV Peptide be stored?
For maximum stability, store lyophilized KPV powder at -20°C, protected from light and moisture. Once reconstituted, store at 2–8°C and use within a reasonable timeframe.

What is the difference between KPV and BPC-157?
KPV is a three-amino-acid fragment of α-MSH studied for inflammation modulation, while BPC-157 is a 15-amino-acid peptide studied for tissue repair. They are investigated for different biological targets .

Is KPV prohibited in sports?
KPV is not specifically named on the WADA Prohibited List, but as an unapproved drug substance, its use would likely fall under the S0 category (non-approved substances) for athletes subject to anti-doping testing .

Research Applications for KPV

Researchers are currently investigating KPV across multiple scientific domains:

• Gastrointestinal research: Studying PepT1-mediated uptake and colonic targeting in inflammation models

• Dermatological studies: Examining effects on keratinocyte inflammation and skin barrier function

• Immunology: Investigating NF-κB pathway modulation and cytokine regulation

• Wound healing models: Exploring epithelial repair mechanisms in preclinical systems

Order KPV Peptide Today

Whether you are studying inflammatory pathways, epithelial biology, or peptide transport mechanisms, KPV from PeptidesUnit.com provides a reliable research tool for your laboratory.

Browse our catalog at PeptidesUnit.com to order KPV and other high-quality research compounds.