CJC 1295 ipamorelin Blend 5mg/5mg (99% Purity) – Research Grade Dual Peptide
Product Overview
The CJC-1295 (No DAC) + Ipamorelin blend is a research-grade combination of two synergistic peptides: a growth hormone-releasing hormone (GHRH) analog and a growth hormone-releasing peptide (GHRP). This dual formulation is designed for laboratory investigation of growth hormone (GH) axis signaling, pulsatile secretion dynamics, and downstream metabolic pathway modulation .
CJC-1295 (No DAC) is a synthetic tetrasubstituted analogue of GHRH (1-29) with amino acid substitutions that enhance stability and resistance to enzymatic degradation compared to native GHRH . The “No DAC” designation indicates the absence of the Drug Affinity Complex, resulting in a shorter half-life that more closely mimics the body’s natural pulsatile GHRH release pattern .
Ipamorelin is a synthetic pentapeptide and selective agonist of the ghrelin/growth hormone secretagogue receptor (GHS-R). It is considered one of the most selective GHRPs, with minimal impact on cortisol, prolactin, or other endocrine pathways .
When combined, these peptides act through complementary receptors to produce a synergistic effect on endogenous GH secretion, making this blend a subject of significant interest in endocrine research, metabolic studies, and models of tissue regeneration .
Mechanism of Action
This dual-peptide blend functions through complementary signaling pathways:
CJC-1295 (No DAC) – GHRH Receptor Activation:
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Binds to GHRH receptors on pituitary somatotroph cells
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Stimulates the synthesis and pulsatile release of growth hormone
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The “No DAC” form produces brief, physiologic GH pulses that emulate natural nocturnal and activity-related hormonal rhythms
Ipamorelin – Ghrelin Receptor (GHS-R) Activation:
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Binds to ghrelin receptors (GHS-R1a) in the hypothalamus and pituitary
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Triggers additional GH release via a distinct pathway
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Highly selective; does not significantly elevate cortisol or prolactin levels
Synergistic Action:
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CJC-1295 amplifies GH pulse strength by increasing the number of GH-secreting cells
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Ipamorelin induces additional GH pulses via ghrelin receptor stimulation
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The combination results in elevated GH and IGF-1 levels compared to either peptide alone
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Brief half-lives preserve pulsatile GH secretion and reduce risk of receptor desensitization
Key Research Applications:
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Endocrine signaling and GH-axis pathway studies
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Pulsatile hormone secretion and circadian rhythm research
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Metabolic regulation and body composition investigations
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Muscle protein synthesis and tissue repair models
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IGF-1 signaling and anabolic pathway research
Product Specifications
| Parameter | Specification |
|---|---|
| Product Name | CJC-1295 (No DAC) + Ipamorelin Blend |
| Synonyms | Mod GRF 1-29 + Ipamorelin, CJC-1295 sans DAC + IPA |
| Component A – CJC-1295 (No DAC) | |
| Molecular Formula | C₁₅₂H₂₅₂N₄₄O₄₂ |
| Molecular Weight | ~3367.9 g/mol |
| Sequence | Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met |
| Component B – Ipamorelin | |
| Molecular Formula | C₃₈H₄₉N₉O₅ |
| Molecular Weight | ~711.9 g/mol |
| Sequence | Aib-His-D-2-Nal-D-Phe-Lys-NH₂ |
| CAS Number (CJC-1295) | 863288-34-0 |
| CAS Number (Ipamorelin) | 170851-70-4 |
| Purity | ≥99% (HPLC Verified, per component) |
| Form | White to off-white lyophilized powder |
| Peptide Content | ≥70% |
| Water Content | ≤5.0% |
| Endotoxin Level | <0.25 EU/mg |
| Storage | -20°C (long-term); 2-8°C (short-term), protected from light |
Quality Assurance
Every batch of the CJC-1295 + Ipamorelin blend undergoes comprehensive analytical testing to ensure maximum purity and research integrity:
| Test | Method | Specification |
|---|---|---|
| Identity | ESI-MS | Matches theoretical mass for both components |
| Purity | RP-HPLC | ≥99% area per component |
| Sequence Confirmation | MS/MS | 100% sequence coverage |
| Water Content | Karl Fischer | ≤5.0% |
| Endotoxin | LAL Test | <0.25 EU/mg |
| Sterility | USP <71> | No growth |
Certificate of Analysis (COA) available upon request.
Storage & Reconstitution Guidelines
Storage Conditions:
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Lyophilized (Long-term): -20°C (≤ -18°C), dry, protected from light and moisture
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Lyophilized (Short-term): 2°C – 8°C (refrigerated)
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Reconstituted: 4°C for up to 7 days; avoid repeated freeze-thaw cycles
Reconstitution Protocol:
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Allow vial to reach room temperature
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Add 1–2 mL of sterile bacteriostatic water or 0.9% sodium chloride solution
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Gently swirl (do not vortex) until fully dissolved
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Allow solution to stand at 4°C for 10-15 minutes for complete reconstitution
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Dispense into individual aliquots to minimize freeze-thaw degradation
Note: Peptides are sensitive to formulation, process, and environmental conditions that may lead to aggregation and degradation.
Important Notice
⚠️ FOR RESEARCH USE ONLY
This product is not intended for human consumption, diagnostic use, therapeutic application, or clinical administration. CJC-1295 and Ipamorelin are research chemicals intended exclusively for in-vitro and laboratory research purposes .
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Not approved by the FDA for human use
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Not a dietary supplement, food additive, or pharmaceutical
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Listed on the WADA Prohibited List (Section S2.2)
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Intended solely for qualified researchers and scientific institutions
By purchasing this product, you confirm that you are a licensed researcher or laboratory professional and agree to use this compound in compliance with all applicable local, national, and international regulations.
Why Choose PeptidesUnit.com?
| Feature | Benefit |
|---|---|
| ✅ Premium Purity | ≥99% HPLC-verified purity per component |
| ✅ Dual-Peptide Blend | Convenient pre-mixed 5mg/5mg ratio |
| ✅ Research-Grade Quality | Manufactured under GMP-aligned conditions |
| ✅ Third-Party Tested | Independent COA for every batch |
| ✅ Secure Packaging | Lyophilized in amber glass vials with tamper-evident seals |
| ✅ Fast Global Shipping | Discreet packaging with real-time tracking |
| ✅ Competitive Pricing | Direct-from-manufacturer pricing |
| ✅ Customer Support | Dedicated research support team |
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CJC-1295 (No DAC) + Ipamorelin Blend 5mg/5mg – ≥99% Purity
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