HMG Peptide (Human Menopausal Gonadotropin) – Research Grade

Product Overview

HMG Peptide (Human Menopausal Gonadotropin) is a research-grade glycoprotein hormone preparation derived from the urine of postmenopausal women. Highly Purified HMG (HP-hMG) contains a 1:1 ratio of Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH) activity, making it a valuable research tool for reproductive endocrinology and ovarian stimulation studies .

The gonadotropins in HMG Peptide play a central role in mammalian reproduction by stimulating follicular development and oocyte maturation in ovarian research models . HP-hMG preparations are widely investigated for their clinical efficacy in assisted reproduction, demonstrating comparable outcomes to recombinant FSH and potential benefits in embryo quality within IVF research settings .

⚠️ Research Context: This product is intended exclusively for in-vitro and laboratory research purposes. It is not approved by the FDA for over-the-counter human use. HMG Peptide

Mechanism of Action

HMG functions through the combined activity of two gonadotropin hormones:

• FSH Action: Stimulates follicular growth and development in ovarian research models by binding to FSH receptors on granulosa cells 

• LH Action: Triggers steroidogenesis and supports follicular maturation through LH receptor activation 

• HP-hMG Composition: Highly purified formulations contain a balanced 1:1 ratio of FSH and LH activity, extracted from the urine of postmenopausal women 

Key Research Applications:

• Controlled Ovarian Stimulation (COS) studies

• Reproductive endocrinology and folliculogenesis research

• Gonadotropin receptor binding and signaling investigations

• Oocyte maturation and embryo quality studies

Product Specifications

Quality Considerations for Research Use

Recent analytical investigations have identified important quality attributes of HP-hMG preparations that researchers should be aware of:

These findings are critical for understanding the quality, safety, and research profile of HP-hMG preparations . HMG Peptide

Storage & Reconstitution Guidelines

Storage Conditions:

• Lyophilized (Long-term): -20°C, protected from light and moisture

• Lyophilized (Short-term): 2°C – 8°C (refrigerated)

• Reconstituted: 4°C for up to 7 days; avoid repeated freeze-thaw cycles

Reconstitution Protocol:

1. Centrifuge vial briefly to bring contents to bottom

2. Add sterile water to achieve desired concentration

3. Gently swirl (do not vortex) until fully dissolved

4. Aliquot for extended storage to avoid repeated freeze-thaw cycles

Important Notice

⚠️ FOR RESEARCH USE ONLY

This product is not intended for human consumption, diagnostic use, therapeutic application, or clinical administration. HMG is a research chemical intended exclusively for in-vitro and laboratory research purposes. HMG Peptide

• Not approved by the FDA for human use outside of prescription clinical settings

• Not a dietary supplement, food additive, or pharmaceutical for over-the-counter purchase

• Intended solely for qualified researchers and scientific institutions

By purchasing this product, you confirm that you are a licensed researcher or laboratory professional and agree to use this compound in compliance with all applicable local, national, and international regulations.

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HMG Peptide – Research Grade
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